National Association of Testing Authorities, Australia
Scope of Accreditation
Australian Genome Research Facility
Site
AGRF – Melbourne MT
Accreditation No.
14332
Site No.
24278
Date of Accreditation
02 Jul 2018
Address
Level 13 , Victorian Comprehensive Cancer Centre , 305 Grattan Street
Melbourne, VIC 3000
Australia
Contact
Miss Melanie O'Keefe
P: +61 (03) 93213727
Availability
Services available to external clients
Supervision
Not Applicable
Scope of Accreditation
AGRF – Melbourne MT
ISO 15189 (2012)
- This facility complies with the relevant National Pathology Accreditation Advisory Council (NPAAC) requirements.
Human Pathology
Service | Product | Determinant |
---|---|---|
Molecular genetics - DNA extraction | Blood; Buccal swabs; Formalin-fixed paraffin-embedded (FFPE) tissues; Saliva | DNA storage for future analyses; Purified PCR product; Viable DNA; Viable DNA for sequencing and other molecular assays |
Molecular genetics - DNA fragment size analysis | Fluorescent-labelled DNA sequencing reaction product | DNA fragment size determination |
Molecular genetics - DNA sequencing | Extracted DNA | Sequenced DNA by Sanger sequencing; Sequenced DNA utilising massively parallel sequencing technologies |
Molecular genetics - Heterozygous loci determinations | Extracted DNA | Nucleic acid analysis for specific variants |
Molecular genetics - Investigation of constitutional genetic variants - Carrier testing - Targeted genes | Blood; Extracted DNA; Mouth swabs | Fragile X syndrome (FRAXA); Nucleic acid analysis for specific variants; Spinal muscular atrophy |
Molecular genetics - Investigation of constitutional genetic variants - Diagnostic testing - Whole exome sequencing studies for inherited (germline) DNA/RNA changes | Extracted DNA | Nucleic acid analysis for unknown variants |
Molecular genetics - Predictive genetic testing - Targeted genes | Buccal swabs; Extracted DNA; Saliva | Polygenic risk score (PRS) - Glaucoma |
Molecular genetics - RNA extraction | Formalin-fixed paraffin-embedded (FFPE) tissues | Purified PCR product; RNA storage for future analyses; Viable RNA; Viable RNA for molecular diagnostics; Viable RNA for sequencing |
Molecular genetics - Screening for an unknown mutation - Microarray analysis for inherited (germline) DNA/RNA changes | Extracted DNA | Nucleic acid analysis for unknown variants |
Molecular genetics - Screening for an unknown mutation - Targeted panels for non-inherited (somatic) DNA/RNA changes | Formalin-fixed paraffin-embedded (FFPE) tissues | RNA; Solid tumours |
Molecular genetics - Screening for an unknown mutation - Whole genome sequencing studies for inherited (germline) DNA/RNA changes | Extracted DNA | Nucleic acid analysis for unknown variants |
Molecular genetics/Cytogenetics - Bioinformatic analysis | DNA sequences; FASTQ files | Primary analysis - Conversion of instrument file to FASTQ or FASTA file; Secondary analysis - Alignment and variant calling |
The only data displayed is that deemed relevant and necessary for the clear description of the activities and services covered by the scope of accreditation.
Grey text appearing in a SoA is additional freetext providing further refinement or information on the data in the preceding line entry.
Accreditation No.
14332
Site No.
24278
Print date
19 Apr 2024
END OF SCOPE