GLP Organisation for Economic Cooperation & Development (OECD) Principles of Good Laboratory Practice (GLP)

The OECD Principles of GLP cover the organisational processes and the conditions under which non-clinical health and environmental studies are planned, performed, monitored, recorded, reported, and retained.


What are the OECD Principles of GLP?

The OECD is an international organisation that works to establish evidence-based international standards and find solutions to a range of social, economic and environmental challenges.

The OECD Principles of GLP are applicable to test facilities performing (non-clinical) studies that will be submitted to authorities for the purposes of assessing the health and environmental safety of chemicals and chemical products.

They also define the responsibilities of test facility management, study director, study personnel and quality assurance personnel operating within a GLP system. In addition, standards concerning the suitability of organisations and equipment to perform studies, the need for standard operating procedures, documentation of raw data, study reports and the archiving of records.

Why are OECD Principles of GLP important?

The OECD Principles of GLP ensure the generation of high quality and reliable test data related to the safety of test items such as pharmaceuticals, pesticides and veterinary drugs. The principles have been created in the context of harmonising testing procedures for the Mutual Acceptance of Data (MAD).

This process also ensures that duplicated testing and barriers to trade can be avoided, time and resources saved, all while improving the protection of human health and the environment.

What industries are suitable for GLP recognition?

Australian recognition by NATA for compliance with the OECD Principles of GLP is available to any Australian facility performing non-clinical health and environmental safety studies for regulatory purposes.

GLP recognition is available for the agribusiness (pesticides; herbicides; veterinary chemicals), pharmaceutical, food, medical devices, cosmetic and industrial chemicals sectors.

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The MAD system helps to avoid conflicting or duplicative national requirements, provides a common basis for co-operation among national authorities and avoids creating non-tariff barriers to trade.

OECD countries to the relevant OECD Council Acts have agreed that studies carried out in accordance with the OECD Test Guidelines and Principles of Good Laboratory Practice in one OECD country must be accepted by other countries which adhere to MAD for assessment purposes. This is the concept of “tested once, accepted for assessment everywhere. *” This saves the chemical industry the expense of duplicate testing for products which are marketed in more than one country. 

*While the receiving government must accept the study, how it interprets study results is its own prerogative.

The NATA Accreditation Criteria (NAC) packages are made up of numerous documents which are available for download.

There are General Accreditation Criteria which apply to all facilities, and Specific Accreditation Criteria tailored for industry sectors and activities.

  1. General NATA Documents
  2. General Accreditation Criteria
  3. Specific Accreditation Criteria

General Accreditation Guidance and Specific Accreditation Guidance documents present information on common technical or operational issues.

  1. General Accreditation Guidance
  2. Specific Accreditation Guidance
  3. General Accreditation Forms

Documents published by the OECD are available from

GLP NATA Accreditation Criteria (NAC) Package

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Benefits of being a NATA accredited organisation

NATA accredits organisations to perform testing and inspection activities for their products and services. This gives consumers the assurance they need to make safe, healthy and reliable choices. When you choose to become NATA accredited, you can be sure of a number of competitive advantages for your business.
NATA members receive a globally-recognised, peer-reviewed and government endorsed accreditation that provides a unique level of assurance to members, their clients and the community.
Our accreditation provides an independent benchmark for technical competence. Receiving NATA accreditation demonstrates to customers your organisation’s commitment to quality, safety and reliability of products and services.
NATA accreditation is both nationally and internationally recognised. This provides a competitive advantage when compared to non-accredited organisations and ensures you are market-ready to capitalise on trade opportunities.
NATA has been training individuals and teams both nationally and internationally for over 20 years and enjoys a global reputation for the quality of its courses and programs. Our active role in international accreditation education has seen us conduct training in over 20 countries.
NATA’s long standing and active involvement with international groups enables our members to gain international recognition for their accreditation and minimises the need for multiple assessments from different suppliers.
NATA provides innovative and timely business solutions that meet the needs of our members and fulfil the expectations of the community. We have the experience and resources to ensure your accreditation provides you and your organisation with unique advantages.