Purpose of the OECD Principles of GLP

The primary objective of the OECD Principles of GLP is to ensure the generation of high quality and reliable data from non-clinical health and environmental safety studies related to chemicals in the framework of harmonising testing procedures for the Mutual Acceptance of Data (MAD).

The OECD Mutual Acceptance of Data (MAD) system saves governments and chemical producers millions of dollars every year by allowing the results of a variety of safety studies done on chemicals and chemical products (e.g. pesticides, pharmaceuticals, veterinary medicines, industrial chemicals and pesticides) to be shared between countries.

This agreement requires that studies be carried out using OECD standards for test methods (OECD Test Guidelines or equivalent) and for data quality (OECD Principles of Good Laboratory Practice - GLP).

Under this agreement data generated by a facility that is in a GLP compliance monitoring program of a country that adheres to the MAD agreement must be accepted in other adherents for the purpose of assessment and other uses relating to the protection of people and the environment.