Royal Prince Alfred Hospital Clinical Neuroscience Laboratories

Site

Royal Prince Alfred Hospital Clinical Neuroscience Laboratories

Accreditation No.

20911

Site No.

25131

Date of Accreditation

20 Feb 1990

Address

100 Mallett Street
Camperdown, NSW 2050
Australia

Contact

Assoc Prof Michael Buckland P: +61 (02) 93510741

Availability

Services available to external clients

Supervision

GX (General)

Scope of Accreditation

Royal Prince Alfred Hospital Clinical Neuroscience Laboratories

ISO 15189 (2022)

  • This facility complies with the relevant National Pathology Accreditation Advisory Council (NPAAC) requirements.

Human Pathology

Service Product Determinant
Anatomical pathology - Tissue pathology - Examination of biopsy material Fresh tissue; Muscle; Nerve biopsy In-vitro contraction test; Nerve conduction studies; Neuromuscular disorders; Review and reporting of biopsy material to identify or exclude morphological abnormalities; Structured reporting
Anatomical pathology - Tissue pathology - Examination of biopsy materialAutopsy material received from Forensic institutes and hospitals. Brain - Whole Presence or absence of Creutzfeldt-Jacob disease
Brain - Whole; Spinal cord Review and reporting of material to identify neurological diseases
Anatomical pathology - Tissue pathology - Immunohistochemical investigation Formalin-fixed paraffin-embedded (FFPE) tissues; Frozen sections of fresh tissue Detection of antigenic targets - Various
Anatomical pathology - Tissue pathology - Skeletal muscle enzyme histochemistry Frozen sections of skeletal muscle Detection of muscle enzyme targets
Molecular genetics - DNA extraction Formalin-fixed paraffin-embedded (FFPE) tissues; Frozen tissue DNA storage for future analyses; Purified PCR product; Sample assessment and identification; Viable DNA; Viable DNA for sequencing; Viable DNA for sequencing and other molecular assays
Molecular genetics - DNA sequencing Formalin-fixed paraffin-embedded (FFPE) tissues; Frozen tissue DNA sequence analysis; Pyrosequencing; Sequenced DNA; Sequenced DNA utilising massively parallel sequencing technologies
Molecular genetics - Genetic testing for chimerism and mosaic gene variants (cancer and somatic mosaicism) - Targeted genes Formalin-fixed paraffin-embedded (FFPE) tissues Copy number variation (CNV); Glioma panel
MGMT promoter methylation analysis
H3f3A mutation analysis
TERT promoter mutation analysis
Isocitrate dehydrogenase IDH1 and IDH2 mutation analysis
Molecular genetics/Cytogenetics - Bioinformatic analysis DNA sequences; FASTQ files; RNA sequences Primary analysis - Conversion of instrument file to FASTQ or FASTA file; Secondary analysis - Alignment and variant calling; Tertiary analysis - Data annotation and interpretation

The only data displayed is that deemed relevant and necessary for the clear description of the activities and services covered by the scope of accreditation.

Grey text appearing in a SoA is additional freetext providing further refinement or information on the data in the preceding line entry.